Diacylglycerol antibody
WebThe generation of diacylglycerol (DAG) is critical for promoting immune cell activation, regulation, and function. Diacylglycerol kinase ζ (DGKζ) serves as an important negative regulator of DAG by enzymatically converting DAG into phosphatidic acid (PA) to shut down DAG-mediated signaling. Consequently, the loss of DGKζ increases DAG levels and the … WebThe diacylglycerol kinases (DGKs) catalyze the phosphorylation of the cell membrane lipid diacylglycerol (DG), which is important in lipid biochemistry and signal transduction into phosphatidic acid. DG-mediated signal transduction downstream of the T cell receptor has been reported to be terminated by DGKζ, 1 of 10 DGK isoforms in most cases.
Diacylglycerol antibody
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WebELISA Kit Principle. Aviva Systems Biology Diacylglycerol ELISA Kit (OKEH02607) is based on a competitive enzyme immunoassay technique. The microtiter well-plate in this … WebDiacylglycerol ELISA Kits. Diacylglycerol ELISA kits are assays designed to detect the compound diacylglycerol (DAG) or related enzymes, such as diacylglycerol transferase (DGAT), diacylglycerol kinase, or diacylglycerol lipase. DAG consists of two fatty acid chains bonded to glycerol molecule through ester linkages.
WebOct 15, 2013 · Signaling downstream of the B cell antigen receptor (BCR) is tightly regulated to enable cells to gauge the strength and duration of antigen-receptor interactions and to respond appropriately. We investigated whether metabolism of the second messenger diacylglycerol (DAG) by members of the family of … WebApr 12, 2024 · Activity assays TAG and diacylglycerol (DAG) hydrolase activity assays were performed in the presence of 25 mM CHAPS as described previously [11] with some modifications. For TAG hydrolase assay, 25 µg of microsomal liver fractions were incubated with 1.67 mM triolein (TAG C18:1; T7140 Sigma-Aldrich) and radiolabeled …
WebAug 21, 2024 · Diacylglycerol kinase (DGK) plays a pivotal role in intracellular signaling pathways in mammals. Activated G protein-coupled receptor activates phospholipase C (PLC) through heterotrimeric G … WebAntibodies directed against pERK1/2 (Thr 202 /Tyr 204), IκBα (both from Cell Signaling Technology), and ERK2 (Santa Cruz Biotechnology) were used for Western blotting …
WebPhysiological activation by light of the Drosophila TRP and TRP-like (TRPL) channels requires the activation of phospholipase Cβ (PLC). The hydrolysis of phosphatidylinositol 4,5, bisphosphate (PIP2) by PLC is a crucial step in the still-unclear light activation, while the generation of Diacylglycerol (DAG) by PLC seems to be involved. In this study, we re …
WebThe protein signaling activities of the glycerolipid diacylglycerol (DAG) form the impetus for the projects described herein. DAG’s governance of cellular functions involves activation of peripheral membrane proteins (PMPs) at bilayer surfaces, which includes the activation of protein kinase C (PKC) to regulate oncogenesis. In addition to enzymatic signal … pork chop garage supply parkerWebPathway Description. Legend. T Cell Receptor (TCR) activation promotes a number of signaling cascades that ultimately determine cell fate through regulating cytokine production, cell survival, proliferation, and differentiation. An early event in TCR activation is phosphorylation of immunoreceptor tyrosine-based activation motifs (ITAMs) on the ... pork chop friday perry\u0027sWebMar 15, 2015 · DGAT2A (Acyl-CoA: Diacylglycerol acyltransferase) is an enzyme which exhibits transferase activity, transferring acyl groups. EC=2.7.8.2. Total proteins (containing 30 ug ) from Chlamydomonas … sharpe financial groupWebThe Mehlis' gland of Opisthorchis viverrini was selectively and intensely immunopositive with an antibody against rat diacylglycerol kinase gamma, and its entire structure with associated ... sharpe finder toolWebApr 10, 2024 · Background Antibody-based therapies blocking the programmed cell death-1/ligand-1 (PD-1/PD-L1) axis have provided unprecedent clinical success in cancer treatment. Acquired resistance, however, frequently occurs, commonly associated with the upregulation of additional inhibitory molecules. Diacylglycerol kinase (DGK) α limits the … pork chop gamingWebDec 1, 2024 · Diacylglycerol kinase δ (DGKδ) is a type II DGK, which catalyzes diacylglycerol phosphorylation to produce phosphatidic acid. DGKδ is expressed in several types of tissues and organs including ... pork chop garlic sauceWebDiacylglycerol antibody LS-C664074 is an unconjugated rabbit polyclonal antibody to Diacylglycerol from human and all species. Validated for ICC, IP and WB. Products pork chop frying pan recipe