High affinity nerve growth factor receptor
Web24 de nov. de 2004 · A high-affinity site, Site1, is always occupied first by the receptor ECD (R1) to form a stable 1:1 hormone-receptor intermediate complex [human GH … Web1 de jul. de 1997 · Nerve growth factor (NGF) is involved in the development and maintenance of the nervous system. NGF binds with high affinity to the extracellular region of the tyrosine kinase receptor TrkA. This ...
High affinity nerve growth factor receptor
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WebThe low-affinity NGF receptor (LNGFR), also known as p75 LNGFR or fast NGF receptor, belongs to the NGFR/TNFR superfamily with four Cys-rich repeats in the extracellular … Web1 de jun. de 2003 · NGF binds to the specific high-affinity tyrosine kinase receptor TrkA. TrkA receptors possess a tyrosine kinase catalytic domain. The structure of the TrkA-NGF complex has recently been published and contains one conserved motif, common to all neurotrophins, and one specific motif for TrkA-NGF binding (5).
WebThe nerve growth factor receptor (Ngfr), alias p75 NT receptor, belongs to the tumor necrosis factor transmembrane receptor superfamily. Ngfr binds to nerve growth … Web7 de fev. de 2010 · High affinity receptor for NGF which is its primary ligand, it can also bind and be activated by NTF3/neurotrophin-3. However, NTF3 only supports axonal extension through NTRK1 but has no effect on neuron survival. Upon dimeric NGF ligand-binding, undergoes homodimerization, autophosphorylation and activation.
Web8.6.4 Hepatocyte Growth Factor Receptors. The high-affinity receptor for HGF is the transmembrane c-Met receptor tyrosine kinase. 880 Originally identified as an activated oncogene in an N-methyl-N′-nitrosoguanidine-treated human osteogenic sarcoma cell line, c-Met is a member of the receptor tyrosine kinase family that possesses significant ... WebMonoclonal Anti-Nerve Growth Factor Receptor (NGFR p75) antibody produced in mouse. clone ME20.4, ascites fluid. View Price and Availability. ... Unlike the high-affinity nerve growth factor tyrosine kinase receptors (TrkA, TrkB and TrkC), NGFR has no intrinsic tyrosine kinase activity.
WebHigh affinity receptor for NGF which is its primary ligand, it can also bind and be activated by NTF3/neurotrophin-3. However, NTF3 only supports axonal extension through NTRK1 but has no effect on neuron survival. Upon dimeric NGF ligand-binding, undergoes homodimerization, autophosphorylation and activation.
WebHuman mast cells express functional TrkA and are a source of nerve growth factor. Eur J Immunol. 1997;27(9):2295–2301. 71. Lambiase A, Bracci-Laudiero L, Bonini S, et al. Human CD4+ T cell clones produce and release nerve growth factor and express high-affinity nerve growth factor receptors. J Allergy Clin Immunol. 1997;100(3):408–414. 72. philips shaving machine amazonWebHigh affinity nerve growth factor receptor EC number EC:2.7.10.1 ( UniProtKB ENZYME Rhea) Alternative names Neurotrophic tyrosine kinase receptor type 1 Slow … philips shb2515 manualWebOvarian cancer is the eighth most common cancer in women worldwide, and epithelial ovarian cancer (EOC) represents 90% of cases. Nerve growth factor (NGF) and its … philips shaving setWebThe mechanisms that influence nerve growth are not known. Nerve growth factor (NGF) and its high-affinity tyrosine kinase receptor A (TrkA) are involved in neural … trx merchant servicesWebUsing in vitro assays, we find that HGF cooperates with nerve growth factor (NGF) in enhancing the axonal growth rate of dorsal root ganglion (DRG) sensory neurons. In … philips shaving trimmer onlineWebNGF mediates its effects by binding to two classes of transmembrane receptors, a high-affinity receptor (tropomyosin-related kinase A, TrkA) and a low-affinity receptor (p75). … philips shb3075bkWeb2 de mai. de 2006 · High affinity nerve growth factor receptor Gene NTRK1 Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 796 Protein existence Evidence at protein level Annotation score 5/5 Entry Feature viewer … trxminf