Phospho irf3

Author: xndu

August undefined, 2024

WebIRF-3 is a member of the interferon regulatory transcription factor (IRF) family. It mediates interferon-stimulated response element (ISRE) promoter activation and functions as a molecular switch for antiviral activity. DsRNA generated during the course of a viral infection leads to IRF-3 phosphorylation on the C-terminal serine/threonine cluster. WebMar 30, 2024 · Similarly, the IRF7, IRF1, and phospho-IRF3 levels hiked after two days of SARS-CoV-2 infection. These findings suggested that IRF7, IRF1, and IRF3 were stimulated following HCoV infections.

Cells Free Full-Text cGAS Regulates the Radioresistance of …

WebApr 23, 2024 · We focused on the phosphorylation of IRF3, which is a downstream factor of the cGAS pathway . As shown in Figure 2A, the expression of phosphorylated-IRF3 (p-IRF3) was increased in HNSCC cells after X-ray irradiation, and cGAS knockdown suppressed the radiation-increased p-IRF3. These results suggest that ionizing radiation activates IRF3 ... Web环保商城会员企业上海邦景实业有限公司提供杂交瘤细胞；tbcd6规格, 细胞名称杂交瘤细胞；tbcd6规格形态特性淋巴母细胞样生长特性半贴壁生长特征特性该细胞属保藏，其特征特性尚未公开。培养条件 flyers ottawa grocery stores

Anti-phospho IRF3 (ser386) Antibody - Sigma-Aldrich

WebIRF-3 can inhibit cell growth and plays a critical role in controlling the expression of genes in the innate immune response. In unstimulated cells, IRF-3 is present in the cytoplasm. … WebIRF3 Antibodies Antibodies that detect IRF3 can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, Flow Cytometry and Peptide array. These antibodies target IRF3 in Human, Mouse, Rat, Non-human primate and Porcine samples. WebPhospho-IRF3 (Ser396) Antibody (720012) in ICC/IF. Immunofluorescence was performed on fixed and permeabilized HeLa cells treated with Calyculin A (50 ng/mL/20 min) for … flyers ottawa canada

Phosphorylation of Ser82 on IRF3 acts as negative ... - ScienceDirect

Phospho-IRF3 (Ser386) Polyclonal Antibody - Thermo Fisher Scientific

WebSep 19, 2013 · IRF3 is a constitutively expressed transcription factor that resides in the cytoplasm and dimerizes and translocates to the nucleus upon phosphorylation ( 6 ). … WebPhospho-IRF3 (S386) ELISA Kit (ab279833) is a very rapid, convenient and sensitive assay kit that can monitor the activation or function of important biological pathways in human cell lysates. By determining phosphorylated IRF3 protein in your experimental model system, you can verify pathway activation in your cell lysates. flyers ouverture boulangerieIRF3 is a member of the interferon regulatory transcription factor (IRF) family. IRF3 was originally discovered as a homolog of IRF1 and IRF2. IRF3 has been further characterized and shown to contain several functional domains including a nuclear export signal, a DNA-binding domain, a C-terminal IRF association domain and several regulatory phosphorylation sites. IRF3 is found … flyers ottawa ontario

"WebPhospho-IRF3 (S386) and Total IRF3 (S386) ELISA Kit (ab279834) is a very rapid, convenient and sensitive assay kit that can monitor the activation or function of important biological pathways in human cell lysates. By determining phosphorylated IRF3 protein in your experimental model system, you can verify pathway activation in your cell lysates. " - Phospho irf3

Phospho irf3

Cells Free Full-Text cGAS Regulates the Radioresistance of …

WebApr 13, 2024 · Antibodies. The following antibodies were used: mouse monoclonal antibodies to α-tubulin (Santa Cruz, sc23948), GAPDH (Santa Cruz, sc32233), phospho-H2A.X (Ser139) (EMD Millipore, 05-636), anti ... WebPhospho-IRF3 (Ser396) Antibody (BS-3195R) in WB Mouse liver lysates probed with Anti-IRF3 (Ser396) Polyclonal Antibody, Unconjugated (bs-3195R) at 1:300 overnight at 4°C. Followed by conjugation to secondary antibody (bs-0295G-HRP) at 1:5000 for 90 min at 37°C. Product Details Target Information

Did you know?

WebInvitrogen Anti-Phospho-IRF3 (Ser385) Polyclonal, Catalog # PA5-36775. Tested in Western Blot (WB) and Immunohistochemistry (Paraffin) (IHC … WebJun 10, 2016 · Each plate also contained positive controls (p65, MAVS, IRF3-5D (constitutively active IRF3), IKK-SE (constitutively active IKK) TRIF),negative controls (pcDNA3.1 vector, GFP, pCherryvectors), emptywells. HEK293T/NF-kB-luciferasecell line high-throughputtrans- fection Fugene6transfection reagent (Roche).

WebAnti-IRF3 (phospho S386) antibody [EPR2346] (ab76493) Research with confidence – consistent and reproducible results with every batch Long-term and scalable supply – powered by recombinant technology for fast …

WebNational Center for Biotechnology Information WebSep 19, 2013 · IRF3 is a constitutively expressed transcription factor that resides in the cytoplasm and dimerizes and translocates to the nucleus upon phosphorylation ( 6 ). Phosphorylated IRF3 induces IFN-β during viral infection, but may also contribute to inflammatory cytokine response to LPS ( 7 ).

WebDetect and quantitate cellular phospho-IRF3 (Ser386) using a homogeneous AlphaLISA® SureFire® Ultra™ assay. We are now two standalone organizations Life Sciences & …

Web"Phospho-IRF3 (Ser396) antibodies" comparison At Proteintech, we pride ourselves on our antibody quality, customer service and transparency. As such, we are comparing our antibodies with other vendors, enabling easy identification and comparisons of key data to help you choose the suitable antibody for your needs. flyers ottawa groceryWebC920001K05Rik; IIAE7; Interferon regulatory factor 3; IRF3; IRF-3; IRF3 (phospho S386); IRF3 (pS386); IRF3 (pSer386); IRF3 phospho; IRF3 phospho S386; IRF3 phospho Ser386; phospho IRF3 Host Species Rabbit green jacket with dressesWebPhospho-IRF-3 (Ser396) Antibody detects endogenous levels of IRF-3 only when phosphorylated at Ser396. This antibody does not cross-react with other family members … Monoclonal Antibody for studying IRF-3 (Ser396) phosphate. Cited in 635 … flyers ottawaWeb55. A method of treating, inhibiting, reducing, ameliorating, and/or preventing a cancer and or metastasis in a subject comprising administering to a subject an adoptive immunothe flyers ottawa this weekWebSep 1, 2024 · To systematically search for the phosphorylation sites on IRF3 in vivo, we carried out tandem affinity purification of recombinant double-tagged IRF3 expressed in HEK293 cells, coupling with mass spectrometric analysis (Fig. 1 A and B). Several phospho-peptides were identified with different color highlighted in the whole amino acid sequence … flyers outlookWebWestern Blot using Phospho-IRF3 (Ser386) Polyclonal Antibody ( Product # PA5-78025 ). Untreated (–) and treated (+) THP-1 whole cell extracts (30 µg) were separated by 10% SDS-PAGE, and the membrane was blotted with Phospho-IRF3 (Ser386) Polyclonal Antibody ( Product # PA5-78025) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody ... flyers owen soundWebIntracellular Delivery of Lipopolysaccharide Induces Effective Th1-Immune Responses Independent of IL-12 Sachiko Watanabe1., Joe Inoue1,2*. 1Department of Biosciences, School of Science and Graduate School of Science, Kitasato University, Japan, 2Department of Immunology and Cell Biology, Graduate flyers outdoor game 2019